Key Takeaways
- Average cold B2B email reply rates in 2025 hover around 5.1%, and cold-calling success sits near 2.3%, so top-performing teams win by out-executing the baseline instead of expecting easy volume wins.
- Prioritize precision over volume: obsess over ICP, relevance, and multithreaded account coverage instead of blasting massive untargeted lists.
- Multichannel, phone-led sequences outperform single-channel outreach by over 2x, while buyers now use 10+ channels to interact with suppliers-your sequences need to match that reality.
- Treat data quality and email deliverability as core strategies, not IT housekeeping, because roughly 17% of cold emails never even make it to the primary inbox.
- Blend AI with human SDRs: use AI for research, personalization, and workflow automation, but let humans own the nuanced conversations and qualification.
- Design your SDR org for focus and leverage-specialization, clear metrics, and strategic use of outsourced SDR pods can easily add 10-20+ qualified meetings per month.
- Bottom line: the top sales strategies for 2025 revolve around relevance, omnichannel execution, AI-augmented SDRs, and a ruthless focus on qualified conversations over vanity activity metrics.
Outbound is getting tougher in 2025: average cold email reply rates sit around 5.1% and cold-calling success hovers near 2.3%. Yet the best B2B teams are still growing pipeline by shifting from volume-first tactics to precision, multichannel outreach, AI-augmented SDRs, and smarter org design. This guide breaks down the data, playbooks, and concrete steps you can use to retool your sales strategy for the new reality.
Introduction
If outbound felt hard in 2023, 2025 probably feels downright hostile.
Cold email reply rates have slid into the low single digits, with the average cold B2B campaign landing around a 5.1% reply rate. Cold-calling success has dropped to about 2.3% of dials turning into meetings. On top of that, 61% of B2B buyers now say they’d rather buy without ever talking to a rep-and 73% actively avoid suppliers who send irrelevant outreach.
So yeah, the old “spray and pray” playbook is dead.
The good news: teams that adapt are still winning big. They’re not sending more messages; they’re sending better ones. They’re not throwing more SDRs at the problem; they’re designing smarter systems, often with AI and specialist partners in the mix.
In this guide, we’ll break down the top sales strategies for 2025 from a B2B sales development perspective-what’s actually working for SDR/BDR teams, what’s broken, and how you can retool your outbound engine to create a predictable pipeline again.
You’ll learn:
- How buyer behavior and channel performance have shifted in the last 12-18 months.
- The specific outbound benchmarks you should be measuring against.
- Battle-tested strategies around ICP, multichannel outreach, deliverability, AI, and SDR org design.
- How a partner like SalesHive can execute these strategies for you if your team is already stretched.
Grab a coffee; let’s fix your 2025 outbound.
The 2025 B2B Sales Landscape: What’s Really Changed
Buyers Are Digital-First, But Still Want Humans for the Hard Stuff
Gartner’s recent research shows that 61% of B2B buyers now prefer a rep-free buying experience overall. That doesn’t mean they hate humans; it means they hate bad sales interactions-especially generic, interruptive outreach that wastes their time.
At the same time, when buying tasks get complex-evaluating fit, navigating internal politics, or configuring a solution-buyers still want a competent human in the mix. They prefer digital self-service for education and basics, then lean on sellers as guides when the stakes go up.
McKinsey’s B2B Pulse backs this up: decision-makers now use 10+ channels to interact with suppliers (double the number from 2016), and 94% say this omnichannel model is as effective or more effective than the old, primarily face-to-face model.
Implication: Your sales strategy in 2025 has to embrace two seemingly opposite truths:
- You’re competing in a digital-heavy, channel-saturated environment.
- Human, high-quality conversations still decide deals-especially in complex B2B.
Channel Benchmarks: Email and Phone in 2025
Let’s level-set expectations.
- Average reply rate for cold B2B emails is ~5.1% in 2025, with many teams stuck lower.
- Roughly 17% of cold emails never even reach the primary inbox, killed off by bounces or spam filters.
- Top performers who get ICP, hooks, and follow-up right are still hitting 15-25% reply rates and 1-2% meeting rates per send.
Phone
- The average cold-calling success rate (dial to booked meeting) is about 2.3% in 2025, down from ~4.8% a year prior.
- Other studies show similar numbers: around 2% of cold calls are successful, but phone still yields higher conversion than email alone.
SDR Activity
- Modern SDRs average around 94 activities per day-calls, emails, voicemails, and social touches.
- That typically translates into just a handful of quality conversations and ~15 meetings per month with ~80% show rates.
All of this is your playing field. If your numbers are worse, you’ve got room to improve. If they’re better, you’re in rare air-protect whatever you’re doing.
Why Traditional Outbound Is Breaking
A few forces are colliding:
- Inbox fatigue: Buyers get flooded with templated sequences that don’t reflect their reality.
- Tougher spam filters: Providers are aggressively cracking down on bulk cold outreach.
- Fragmented attention: Buyers split time across email, Slack, LinkedIn, Teams, and internal tools.
- Rising expectations: B2B buyers expect the same level of personalization and relevance they get in B2C experiences.
The result: average metrics sink, and the teams that cling to old volume tactics find themselves burning domains, burning reps, and burning through their TAM.
The teams that win in 2025 are doing a few things differently.
Strategy #1: Precision Over Volume in Outbound Targeting
Let’s start with the unpopular truth: your outbound problem probably isn’t just copy-it’s who you’re going after and why.
When 73% of B2B buyers say they actively avoid suppliers who send irrelevant outreach, blasting generic campaigns at massive lists is more than just ineffective; it’s brand damage.
Tighten Your ICP Until It Hurts
Most companies’ ICPs are vague: “mid-market SaaS in North America” or “manufacturers with 100-5,000 employees.” That’s not an ICP; that’s a census.
In 2025, winning outbound teams define ICPs with pain-specific clarity:
- Firmographics: industry subsegment, size bands that align with your deal structure.
- Technographics: key tools or platforms that indicate compatibility or pain (e.g., they run Salesforce + Outreach, or an outdated ERP).
- Trigger events: funding, leadership changes, product launches, regulatory shifts.
- Maturity markers: size of SDR team, presence of RevOps, number of locations, etc.
Then they say no to prospects outside that band.
Multi-Thread Accounts From Day One
Another 2025 reality: deals are decided by buying committees. Your email to one VP is only one vote.
Best-practice targeting means:
- Mapping 3-7 stakeholders per account (economic buyer, champions, users, influencers).
- Splitting ownership across SDRs where needed for strategic accounts.
- Using different angles per persona: CFO cares about efficiency and ROI; VP Sales cares about ramp and pipe coverage; RevOps cares about clean process and data.
Instead of 1,000 random contacts, you might work 150-200 accounts deeply, with 3-5 contacts per account and real context.
Practical Play: The “ICP Sprint”
If your targeting is fuzzy, run a 2-week sprint:
- Pull your last 12-24 closed-won deals with healthy CAC and LTV.
- Interview AEs and CSMs: what pain did they solve, what signals predicted success, who was in the deal?
- Build an ICP scorecard (5-10 attributes) and score both wins and losses.
- Use this to prune your outbound universe and instruct list builders or your SDR outsourcing partner.
You’ll probably shrink your list-but your reply and meeting rates will thank you.
Strategy #2: Multichannel, Phone-Led Sequences
Outbound teams that cling to “email-only” cadences are fighting with one hand tied behind their backs.
Buyers now engage with suppliers across ten or more channels, and omnichannel is considered as effective or better than pre-COVID models by 94% of decision-makers. On the SDR side, campaigns combining email, LinkedIn, and phone are seeing results over 2-3x higher than single-channel outreach.
Why the Phone Still Punches Above Its Weight
Yes, cold calling is hard. Yes, average success is around 2.3%. But it’s still one of the only channels that gives you real-time discovery and objection handling.
A well-run phone motion in 2025 looks like this:
- Verified data: Use a reliable data provider or a partner like SalesHive that validates direct dials before calling.
- 3-5 intentional call attempts per contact: data shows most productive conversations happen by the third call; beyond five, the returns drop sharply.
- Frameworks, not rigid scripts: reps follow a structure (pattern interrupt, value, question) but adapt language in real time.
- Clean handoffs: calls convert into well-documented booked meetings with clear context for AEs.
Sample 15-Touch Multichannel Cadence (21-24 Days)
Here’s a skeleton you can adapt:
- Day 1, Email #1 (short, highly relevant) + LinkedIn profile visit.
- Day 2, Call #1 + voicemail (if no answer) referencing the email.
- Day 3, LinkedIn connection request (no pitch, just context).
- Day 5, Email #2 (different angle, social proof) + Call #2.
- Day 7, LinkedIn follow-up message (if connected) with a question.
- Day 10, Call #3 + voicemail focused on a specific pain.
- Day 12, Email #3 (content share-case study, benchmark, or quick loom).
- Day 16, Call #4 (if still uncontacted) targeting another stakeholder.
- Day 20, Breakup email-polite, concise, with a clear CTA.
Every touch has a job: provoke a conversation, not just “check in.”
How SalesHive Runs Multichannel in Practice
A multichannel motion is exactly how SalesHive’s SDR pods operate. They combine cold calling with personalized email (using their AI-powered eMod engine) and social touches to create multiple paths into an account. Their specialists split roles-researchers, email customizers, and callers-so that each touch is high quality instead of one rep juggling everything poorly.
Even if you’re not outsourcing, you can steal the structure: specialize within your SDR team and design cadences that intentionally orchestrate channels instead of treating them as random tools.
Strategy #3: Protect Deliverability and Data Quality Like Revenue
You can’t fix what you can’t land.
When roughly 17% of cold emails never make it to the primary inbox, domain reputation and data quality stop being “ops problems” and become core parts of your sales strategy.
Email Infrastructure: The Boring Stuff That Makes You Money
At a minimum, your outbound program in 2025 should have:
- Proper authentication: SPF, DKIM, and DMARC set up correctly for every sending domain.
- Domain warm-up: new domains gradually ramped from tens to hundreds of emails per day, not thousands on day one.
- Send limits per domain: cap daily cold email volume (often 200-300/day/domain) to stay under the radar.
- List validation: regular cleansing of bounced and invalid emails before every major campaign.
- Engagement-based throttling: slow or pause sequences on domains that show declining opens and replies.
If you don’t have internal RevOps for this, this is exactly where a specialist agency earns its keep-they live in these settings every day.
Data Quality: Garbage In, Garbage Out
The average SDR only spends a fraction of their day actively selling; the rest gets chewed up by research, admin, and bad data. Studies show that when B2B sales reps work with specialist agencies and good data tools, they can spend over 70% of their time pitching and closing instead of cleaning lists.
Data quality tactics that matter in 2025:
- Centralize your contact data in one system or platform to avoid duplicates and version conflicts.
- Standardize key fields (industry, role, region, company size) so you can slice and target accurately.
- Score accounts and contacts based on ICP fit and engagement, then prioritize outreach accordingly.
- Run regular data hygiene cycles-monthly or quarterly-where you purge or update stale records.
SalesHive bakes this into their own platform, validating contact data and running checks before campaigns launch so SDRs spend their time in conversations, not spreadsheets.
Put Deliverability and Data on the Scoreboard
If you want your team to care, measure it. Add a few KPIs to your regular reviews:
- Domain- or mailbox-level delivered rate for outbound.
- Bounce rate per list source.
- Spam complaint rate (where visible).
- Percentage of accounts with complete key fields in CRM.
Once these are visible, they’ll start to improve.
Strategy #4: AI-Augmented SDRs, Not AI-Only Funnels
If you’re not using AI in your sales development motion yet, you’re behind-but not in the way you might think.
Gartner expects that by 2030, 75% of B2B buyers will still prefer sales experiences that prioritize human interaction over AI. Buyers appreciate speed and convenience, but they’re already pushing back on interactions that feel uncanny or robotic.
So the play is not “replace SDRs with bots.” It’s give SDRs superpowers.
Where AI Shines in Sales Development
Here’s where AI earns its seat in 2025 SDR workflows:
- Research summarization, Feed it a prospect’s LinkedIn, website, and recent news; get a tight, 3-5 bullet brief for call prep.
- First-draft personalization, AI drafts a short opening line or paragraph tying your offer to a specific signal (new role, funding, tech stack). Reps approve and tweak.
- Prioritization and lead scoring, AI analyses firmographic, technographic, and engagement data to suggest who to hit today.
- Call notes and CRM updates, Transcribe calls and auto-generate summaries, next steps, and fields for reps to confirm.
The goal: give each SDR more at-bats without sacrificing relevance.
Human Sellers Still Own the Hard Parts
There are parts of sales development AI is flat-out bad at today:
- Reading the room when a prospect is skeptical or political.
- Surfacing latent pains that aren’t in any data source.
- Deciding when to walk away from a bad-fit “opportunity.”
Those are human jobs, and they’re more important as buyers get savvier.
SalesHive leans into this hybrid model. Their AI tools (including eMod for email personalization and an in-house platform for campaign orchestration) do the heavy lifting on data and content. Their SDRs-US-based and Philippines-based-focus on high-quality conversations and qualification.
If you’re building in-house, steal the blueprint: let AI write drafts and highlight targets; let humans decide who to pursue and how to steer the talk.
Strategy #5: Design Your SDR Org for Focus and Leverage
Most outbound programs don't fail because reps are lazy. They fail because the system around the reps is incoherent.
Specialize to Increase Throughput
Top-performing orgs borrow from the assembly-line model:
- Researchers / list builders, Focus on ICP fit and data quality.
- SDRs / BDRs, Own conversations and meetings booked.
- RevOps / program managers, Own sequences, tooling, and reporting.
SalesHive literally structures their service this way: you get researchers, email customizers, and callers, each optimized for their piece of the pipeline. You can recreate a version of that internally, even with a small team.
Measure What Actually Matters
In 2025, smart SDR leaders are shifting metrics away from “activity for activity’s sake” to quality-weighted performance.
Consider tracking:
- Activities per day (as a guardrail, not the goal).
- Conversations per day (defined and logged consistently).
- Meetings booked and held per rep.
- Meeting-to-opportunity conversion (by rep, by segment, by channel).
- Opportunity-to-close for SDR-sourced opportunities.
Once you have these, you can back into realistic activity expectations instead of guessing.
When to Bring in an Outsourced SDR Partner
Sometimes the best “org design” decision is to not build everything yourself.
Outsourcing SDRs makes particular sense when:
- You’re entering a new market or vertical and want to test traction quickly.
- You don’t have internal expertise to design sequences, infra, and playbooks.
- You’re constrained on hiring but need pipeline now.
Providers like SalesHive offer:
- US-based and Philippines-based SDRs so you can match budget with complexity.
- Their own AI-enabled platform for campaigns, reporting, and list building.
- Month-to-month contracts and risk-free onboarding so you can treat it as a 90-day experiment instead of a multi-year bet.
A common play is to give an outsourced pod one clear segment-say, Series B SaaS in North America or industrial manufacturers in the Midwest-and compare their performance and cost per meeting against your in-house team.
If they win, you scale. If they don’t, you’ve bought learning and sequences you can repurpose internally.
How This Applies to Your Sales Team (90-Day Rebuild Plan)
Let’s take this from theory to something you can actually run.
Days 1-15: Diagnose and Align
- Pull your funnel metrics for the last full quarter:
- Email: delivered, open, reply, positive reply, meeting rates.
- Phone: dials, connects, conversations, meetings.
- SDR productivity: activities, meetings, opportunities.
- Compare to 2025 benchmarks from this guide so you know where you’re behind or ahead.
- Run an ICP workshop with sales, marketing, and customer success. Rewrite your outbound ICP and disqualifiers.
- Decide where to focus: targeting, messaging, channel mix, or rep skills. Don’t try to fix everything in one sprint.
Days 16-45: Build and Pilot New Plays
- Design one new multichannel cadence for your top ICP segment and primary persona.
- Fix your foundations in parallel: domain warm-up, SPF/DKIM/DMARC, list validation, and CRM field standardization.
- Pilot AI tools in a narrow scope (e.g., research summaries and first-line personalization) with one pod of SDRs.
- Coach hard on calls: record and review 3-5 cold calls per rep per week focused on intros, discovery questions, and objection handling.
Days 46-75: Scale What Works, Cut What Doesn’t
- Compare performance of the new cadence vs your legacy one-reply rates, meetings, and opportunities.
- Roll out winning elements across other segments; sunset sequences and tactics that are clearly underperforming.
- Clean up your metrics: align how you define and log conversations, meetings, and stages so reporting is apples-to-apples.
- If needed, bring in an outsourced SDR pod (e.g., from SalesHive) to cover a new region or segment using your updated ICP and messaging.
Days 76-90: Lock In the System
- Document your outbound operating system: ICPs, cadences, talk tracks, data rules, and dashboards.
- Formalize weekly rituals: pipeline review, call review, and campaign performance review.
- Set quarterly targets tied to the right metrics-meetings, opportunities, and revenue-not just activity.
- Plan your next experiment: new channel (events, direct mail), new persona, or deeper AI integration.
After 90 days, you won’t have a perfect engine-but you’ll have a modern, data-backed, multi-channel outbound motion that can actually compete in 2025.
Conclusion: What Top Sales Strategies in 2025 Really Have in Common
If you strip away the buzzwords, the top B2B sales strategies in 2025 share a few simple traits:
- Relentless relevance, Tight ICPs, contextual hooks, and buyer-centric messaging.
- Omnichannel reality, Phone, email, and social working together, not in silos.
- Strong foundations, Clean data, healthy domains, and clear processes.
- Human + AI collaboration, Automation where it helps, humans where it counts.
- Smart resourcing, Specialized roles and, when it makes sense, outsourced SDR pods that bring expertise and scale.
The market has raised the bar, but it hasn’t made outbound impossible. It’s just punished lazy, generic, high-volume tactics.
If you want help executing this playbook instead of building it all yourself, that’s where SalesHive comes in. Since 2016, they’ve helped hundreds of B2B companies book over 100,000 meetings using exactly the strategies we’ve been talking about-cold calling, email outreach, SDR outsourcing, and list building, all supported by AI.
Whether you build in-house, partner with a specialist, or (ideally) do both, the mandate for 2025 is the same: stop chasing superficial volume and build a system that consistently creates real, qualified conversations with the right buyers.
That’s how you win this year-and next.
📊 Key Statistics
Expert Insights
Stop Playing the Volume Game—Play the Relevance Game
In 2025, blasting big lists is a fast way to tank your domain reputation and annoy your market. Tighten your ICP, build smaller, high-intent lists, and insist every touch includes a concrete reason for outreach. You'll see fewer sends, more replies, and way better meetings.
Make the Phone the Spine of Your Cadence
Cold email alone can't carry pipeline anymore. Anchor your sequences around well-planned call blocks, with email and LinkedIn supporting the conversation before and after calls. Phone-first cadences, with 3-5 quality call attempts per account, consistently beat email-only approaches in meetings booked.
Treat Deliverability Like a Core KPI, Not an IT Problem
If your emails never hit the inbox, nothing else matters. SDR leaders should own sender reputation, warm-up processes, list validation, and spam-score monitoring the same way they own meetings and pipeline. Make deliverability a weekly dashboard item in your sales meetings.
Use AI as a Force Multiplier, Not a Crutch
AI can handle research, draft personalization, and suggest next best actions, but it can't replace human judgment on qualification and discovery. Train SDRs to use AI for prep and personalization, then coach them hard on live conversations and deal sense-making.
Outsource for Focus, Not Abdication
Outsourced SDR teams work best when they plug into a clear ICP, messaging, and qualification framework-not when you throw the whole problem over the fence. Keep strategy and feedback loops in-house, and let a specialist partner handle the grind of execution and experimentation.
Action Items
Audit your current outbound funnel against 2025 benchmarks.
Compare your open, reply, connect, and meeting rates to current industry data, then prioritize the biggest gaps. Use this to set realistic goals and decide where to focus-targeting, messaging, channel mix, or rep skills.
Redefine and tighten your ICP for outbound.
Sit down with sales, marketing, and customer success to list out your best-fit segments, firmographics, technographics, and trigger events. Turn that into a simple, written ICP checklist SDRs and list builders must follow.
Design one net-new multichannel cadence per core persona.
Map a 15-20 touch sequence over 3-4 weeks that combines phone, email, LinkedIn, and voicemail, and clearly define the purpose of each touch. Test it for one segment before rolling out broadly.
Invest a sprint in fixing your data and deliverability foundations.
Run your domains through deliverability tools, clean bounced/invalid contacts, and standardize data fields in your CRM. Assign a specific owner-often the SDR or RevOps manager-for ongoing health checks.
Layer AI into the SDR workflow where it actually helps.
Pilot AI tools for pre-call research summaries and first-draft personalization, then train reps on editing for clarity and voice. Track time saved and any lift in reply or meeting rates over 30-60 days.
Run a 90-day experiment with an outsourced SDR pod.
Pick one segment (e.g., a new vertical or region) and give a partner like SalesHive clear ICP, messaging, and success metrics. Compare cost per meeting and pipeline generated against your in-house benchmarks.
Partner with SalesHive
SalesHive is a US-based B2B lead generation agency, founded in 2016, that lives and breathes modern outbound. They’ve booked 100,000+ meetings for 1,500+ clients by combining cold calling, email outreach, SDR outsourcing, and industrial-strength list building into one cohesive engine. Instead of handing you a generic playbook, they plug in specialized SDR pods (US-based and Philippines-based) that run multichannel campaigns-phone, email, and LinkedIn-against a tightly defined ICP.
On the email side, SalesHive’s AI-powered tools, including their eMod engine, handle deep personalization at scale while protecting deliverability. On the phone side, professionally trained SDRs work proven frameworks to turn cold calls into qualified meetings, not random demos. All of this is wrapped in month-to-month, no-annual-contract pricing and risk-free onboarding, so you can test outbound in a segment or territory without betting the whole year’s budget. If you want the 2025 best practices in this guide executed for you, SalesHive is built to do exactly that.
❓ Frequently Asked Questions
What's a 'good' cold email reply rate for B2B in 2025?
Baseline reply rates for cold B2B email in 2025 sit around 3-5.1%, depending on industry and list quality. If you're under 2%, you almost certainly have targeting, messaging, or deliverability problems. Well-run, highly personalized campaigns frequently hit 8-15% or more, especially when paired with tight ICPs and multichannel touches. Treat 5% as table stakes and 10%+ as top-tier performance, not a unicorn.
Is cold calling still worth it when average success is only ~2.3%?
Yes-if you do it right. A 2.3% dial-to-meeting rate can be very profitable when your ACV is healthy and the targeting is tight. The phone is also the only channel that gives immediate feedback and lets SDRs shape the conversation. Teams that work verified data, use strong frameworks, and make 3-5 call attempts per account routinely outperform the averages and feed a lot of pipeline to AEs.
How many touchpoints should a modern outbound cadence include?
Most B2B buying committees are distracted and risk-averse, so you're rarely getting traction in 1-2 touches. Current data suggests 5-12 touchpoints is where most replies happen, with many replies coming from later follow-ups rather than the first email. For cold outbound, 15-20 touches across 3-4 weeks-balanced across phone, email, LinkedIn, and voicemail-is a solid starting point, assuming every touch adds some new value or angle.
How should we balance inbound and outbound in 2025?
Inbound still converts at much higher rates and lower cost than cold outbound, so you should treat inbound leads like gold-fast follow-up, tailored responses, and clear next steps. Outbound's job is to create net-new conversations with ideal accounts you'd never see otherwise and to activate demand around upcoming initiatives. Practically, many teams split SDR time with 20-30% dedicated to inbound SLAs and 70-80% on structured outbound programs.
Where does AI fit into an SDR or BDR's workflow today?
AI is best used as a copilot, not a replacement. In B2B sales development, the sweet spots are research synthesis (turning a prospect's LinkedIn and website into a quick brief), first-draft email personalization, list enrichment, and helping reps prioritize which accounts to hit today. Live conversations, real qualification, objection handling, and deal strategy still belong squarely to humans, especially as complex buyers push back on overly robotic interactions.
When does it make sense to outsource SDRs versus building everything in-house?
Outsourcing makes the most sense when you need to launch or scale outbound quickly, test new markets, or don't have the internal expertise to build a strong SDR program. A specialist partner brings established playbooks, tech, and management. In-house often makes sense once outbound is proven, your ICP is dialed, and you're ready to invest heavily in culture and long-term SDR career paths. Many teams run a hybrid: core SDRs in-house plus outsourced pods for experimentation and overflow.
What are realistic productivity expectations for an SDR in 2025?
Modern outbound is harder than it was a few years ago, so pure activity numbers can be misleading. Data shows average SDRs making around 90-100 activities per day across calls, emails, and social, generating roughly 3-5 quality conversations and 10-20 meetings per month depending on ACV and motion. What matters more is conversation quality, meeting acceptance, and opportunity conversion-if those are healthy, you can adjust activity levels up or down.
How do we know if our sequences are actually working, not just 'busy'?
Look beyond opens and raw replies. Track reply rate, positive reply rate, meeting-booked rate per contact, and opportunity conversion from meetings touched by a given sequence. Compare those to your baselines and to other sequences targeting similar segments. If a cadence has decent reply volume but weak meeting or opportunity conversion, you likely have a messaging or qualification issue. If everything is low, revisit targeting and channel mix first.